Behavioral profiles displayed by rats in an elevated asymmetric plus-maze: effects of diazepam
نویسندگان
چکیده
منابع مشابه
Behavioral profiles displayed by rats in an elevated asymmetric plus-maze: effects of diazepam.
When rats are exposed to unknown environments where novelty and fear-inducing characteristics are present (conflictive environments), some specific behaviors are induced and exploration is apparently modulated by fear. In our laboratory, a new type of plus-maze was designed as a model of conflictive exploration. The maze is composed of four arms with different geometrical characteristics, diffe...
متن کاملAn Assessment of Changes in Open-Field and Elevated Plus-Maze Behavior Following Heat Stress in Rats
This paper presents the effect of high environmental heat on behavior of the male Charles Foster rats. Eighty rats were divided into three groups, subjected to (i) acute heat stress (ii) chronic heat stress and (iii) handling control group. Animals were exposed to the hot environment in a biological oxygen demand incubator at 38 ± 1ºC (relative humidity 45-50%) for four hours of continuous sing...
متن کاملModulation of Anxiety-Like Behavior in Sildenafil Citrate-Treated Mice Placed in an Elevated Plus-Maze
Introduction: Sildenafil, a phosphodiesterase-5 (PDE5) inhibitor, may have various effects on the central nervous system via the nitric oxide (NO)-cyclic guanosine monophosphate (cGMP) pathway. Preclinical studies have shown the controversial effect of sildenafil on anxiety-like behavior in animals. This study was undertaken to investigate the acute effect of sildenafil on anxiety-like behavior...
متن کاملBehavioral effects of "vehicle" microinjected into the dorsal periaqueductal grey of rats tested in the elevated plus maze.
To investigate the behavioral effects of different vehicles microinjected into the dorsal periaqueductal grey (DPAG) of male Wistar rats, weighing 200-250 g, tested in the elevated plus maze, animals were implanted with cannulas aimed at this structure. One week after surgery the animals received microinjections into the DPAG of 0.9% (w/v) saline, 10% (v/v) dimethyl sulfoxide (DMSO), 2% (v/v) T...
متن کاملanxiolytic effect of ocimum basilicum extract in rats tested by elevated plus-maze task
conclusions our results demonstrated that the extract of ob could induce anxiolytic effect in rats after 1 week oral administration. the effect of ob was not induced through changes in motor activity. further investigations are necessary for pharmacological providing of ob and better understanding of its anxiolytic properties and neurobiological mechanisms. results the results showed that after...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Brazilian Journal of Medical and Biological Research
سال: 1999
ISSN: 0100-879X
DOI: 10.1590/s0100-879x1999000100015